2024

F. S. Mesquita*, Abrami L, Forey R, Kunz B, Raclot C, Bracq L, Martins F, Milanovic D, Planet E, Rosspopoff O, Trono D, van der Goot FG* et al. accepted (Nature Communications). BioRXiv preprint Identification of the LORD pathway: epigenetically controlled response to lipid oxidation. *co-correspondence

F. S. Mesquita, Laurence Abrami, Maurine E. Linder, Shernaz X. Bamji, Bryan C. Dickinson, and F. Gisou van der Goot (2024) - Mechanisms and functions of protein S-acylation. Nat Rev Mol Cell Biol

2023

 F. S. Mesquita*, L. Abrami, Arthur Samurkas and F. G. van der Goot* (2023) - S-acylation: an orchestrator of the life cycle and function of membrane proteins. FEBS Journal. *co-correspondence

F. S. Mesquita*, L. Abrami, L. Bracq, N. Panyain, V. Mercier, B. Kunz, A. Chuat, J. Carlevaro-Fita, D. Trono, and F. G. van der Goot* (2023) - SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase. Nature Communications. *co-correspondence.

P. A. Sandoz, R. A. Denhardt-Eriksson, L. Abrami, L. A. Abriata, G. Spreemann, C. Maclachlan, S. Ho, B. Kunz, K. Hess, G. Knott, F. S. Mesquita*, V. Hatzimanikatis*, *F. G. van der Goot (2023) - Dynamics of CLIMP-63 S-acylation control ER morphology. Nature Communications, *co-correspondence

Brito, C.; Pereira, J.M.; Mesquita, F.S.; Cabanes, D.; Sousa, S. (2023) - Src-Dependent NM2A Tyrosine Phosphorylation Regulates Actomyosin Remodeling. Cells (MDPI)

2022

M. U. Anwar, O. A. Sergeeva, L. Abrami, F.S. Mesquita, I. Lukonin, T. Amen, A. Chuat, L. Capolupo, P. Liberali, G. D’Angelo, F. Gisou van der Goot (2022) - ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains Developmental Cell

*C. Odendall, *J Sa-Pessoa, *F. S. Mesquita (2022) - Meeting report – Cell dynamics: host–pathogen interface. J Cell Sci. *co-correspondence.

Figueiredo J, Henriques MX, Catalão MJ, Pinheiro S, Narciso AR, Mesquita F, Saraiva BM, Carido M, Cabanes D, Pinho MG, Filipe SR. (2022) Encapsulation of the septal cell wall protects Streptococcus pneumoniae from its major peptidoglycan hydrolase and host defenses. PLoS Pathog.

2021

F.S. Mesquita*, L. Abrami, O. Sergeeva, P. Turelli, E. Qing, B. Kunz, C. Raclot, J. Paz Montoya, L.A. Abriata, T. Gallagher, M. Dal Peraro, D. Trono, G. D’Angelo, *F. G. van der Goot. S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity. Developmental Cell, 56 (2021), pp. 2790-2807,https://doi.org/10.1016/j.devcel.2021.09.016. *co-correspondence.

Abrami, L., Audagnotto, M., Ho, S MJ Marcaida, F. S. Mesquita, M. U. Anwar, P. A. Sandoz, G. Fonti, F. Pojer, M. Dal Peraro & F. G. van der Goot (2021). Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains. Nat Chem Biol

2020

FS Mesquita*, FG van der Goot, OA Sergeeva*. (2020) Mammalian membrane trafficking as seen through the lens of bacterial toxins. Cellular Microbiology. *co-correspondence

Patents

EPO Family ID: 79927550 “Inhibitors of acyl protein thioesterases against microbial infections”- F.S. Mesquita, L. Abrami, F. G. van der Goot (all co-applicants 25%); C. Tapparel and V. Cagno UNIGE-CMU (12.5%) filed Jan 23rd, 2023.

before 2019

C Brito, FS Mesquita, CKE Bleck, JR Sellers, D Cabanes, S Sousa (2019). Perfringolysin o-induced plasma membrane pores trigger actomyosin remodeling and endoplasmic reticulum redistribution Toxins

Brito C, Cabanes D, Mesquita FS*, Sousa S* (2018) Mechanisms protecting host cells against bacterial pore-forming toxins attack – Cellular and Molecular Life Sciences. *co-correspondence

Mesquita FS*, Brito C, Cabanes D, Sousa S* (2017) Control of cytoskeletal dynamics during cellular responses to pore forming toxins. Communicative & Integrative Biology, 10:5-6, (*co-correspondence)

Mesquita FS, Brito C, Mazon Moya MJ, Pinheiro JC, Mostowy S, Cabanes D, Sousa S (2017) Endoplasmic reticulum chaperone Gp96 controls actomyosin dynamics and protects against pore-forming toxins. EMBO Reports 18: 303-318

Almeida MT, Mesquita FS, Cruz R, Osorio H, Custodio R, Brito C, Vingadassalom D, Martins M, Leong JM, Holden DW, et al. (2015) Src-dependent Tyrosine Phosphorylation of Non-muscle Myosin Heavy Chain-IIA Restricts Listeria monocytogenes Cellular Infection. Journal of Biological Chemistry 

Sousa S, Mesquita FS, Cabanes D. (2014) Old war, new battle, new fighters! Journal of Infectious Diseases.

Mesquita, F. S., Holden, D. W. & Rolhion, N. (2013) Lack of effect of the Salmonella deubiquitinase SseL on the NF-kappaB pathway, PloS one.

Thomas, M., Mesquita, F. S. & Holden, D. W. (2012) The DUB-ious lack of ALIS in Salmonella infection: a Salmonella deubiquitinase regulates the autophagy of protein aggregates, Autophagy.

Mesquita, F. S., Thomas, M., Sachse, M., Santos, A. J. M., Figueira, R. & Holden, D. W. (2012) The Salmonella deubiquitinase SseL inhibits selective autophagy of cytosolic aggregates, PLoS pathogens

Santos, J. M., Freire, P., Mesquita, F. S., Mika, F., Hengge, R. & Arraiano, C. M. (2006) Poly(A)-polymerase I links transcription with mRNA degradation via sigmaS proteolysis, Molecular Microbiology.